Course OutlineOverviewRad226A is the first half of a two-course sequence covering fundamental principles of magnetic resonance imaging (MRI) and spectroscopy (MRS) focusing on the analytic tools needed to understand interactions among nuclear spins and how these interactions give rise to the signals and image contrast observed from in vivo studies. Following a review of classical MRI, we’ll cover the quantum mechanical description of NMR, which provides deeper insights into nuclear spin physics. We’ll then study J-coupling, the most mathematically tractable coupling mechanism, and its fundamental importance in MRS. In Part II (Rad 226B), we will extend these concepts to develop the NMR relaxation theory needed to analyze the behavior of spin-spin and spin-lattice couplings in the presence of in vivo molecular tumbling and chemical exchange. This theory provides the foundation for analyzing multiple in vivo MRI contrast mechanisms and contrast agents. This Outline may be updated during the course. OutlineSection A: Introduction and MRI Review
Section B: Quantum Mechanics
Section C: Spin Physics
Section D: Pulse Sequence Examples
Section E: In Vivo Spectroscopy
Section F: Special Topics
Important DatesSee Schedule |