Untitled Document

ALL IS FAIR IN LOVE AND WARTS

(Title by Bob Siegel)

Created by Pablo Josue Pozo and Jessika Diaz

Created Fall 2005

	Human Papillomavirus
Morphology	and	Genome
*3	Meet the culprit: The papillomavirus particle is about 55nm in diameter and has a DNA double-stranded, covalently closed, monopartite, circular genome of about 8000bp. All of the genomic information is located on one strand. The genome is divided into an early region that has eight open reading frames (ORFs E1–E8), a late region that has two ORFs (L1 and L2), and a noncoding long control region (LCR), which contains regulatory elements for viral DNA replication and transcription. The virion is icosahedral and is unenveloped with a spherical shape.	*4

Plantar and Common Warts--HPV 1,2, and 4	Anogenital warts--HPV 6, 11	HPV-16,18 and Cervical Cancer

Drug Profile				March 2004 Papillomavirus Humans and Viruses Webpage
*2	Primary References	*5	Other Weblinks	*2
		Pathogen Cards

		New and HOT Findings

Acknowledgement: Thanks for the motivation given by the Humans and Viruses Course taught by Dr. Robert Siegel at Stanford University.

Picture Referenes: 1) Oxford Textbook of Medicine 2) http://web.uct.ac.za/depts/mmi/stannard/papillo.html 3) http://www.hawaii.edu/pceidr/images/papillomavirus.gif 4) http://bilbo.bio.purdue.edu/~baker/icons/proj_pics/papova/papilloma/hpv_1L1L2_big.gif 5) http://www.york.ac.uk/depts/biol/units/cru/HPVpic1small.jpg