Publications

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Nusse R. "The Wnt gene family in tumorigenesis and in normal development." J Steroid Biochem Mol Biol. 1992;43:9-12. Abstract
Nusse R, Asselbergs FA, Salden MH, Michalides RJ, Bloemendal H. "Translation of mouse mammary tumor virus RNA: precursor polypeptides are phosphorylated during processing." Virology. 1978;91:106-115.
Nusse R, Varmus H. "Three decades of Wnts: a personal perspective on how a scientific field developed." The EMBO journal. 2012;31(12):2670-84. Abstract
Nusse R. "Patching up Hedgehog." Nature. 1996;384:119-120.
Nusse R, van Ooyen A, Rijsewijk F, van Lohuizen M, Schuuring E, van't Veer L. "Retroviral insertional mutagenesis in murine mammary cancer." Proc R Soc Lond B Biol Sci. 1985;226:3-13. Abstract
Nusse R, Janssen H, de Vries L, Michalides R. "Analysis of secondary modifications of mouse mammary tumor virus proteins by two-dimensional gel electrophoresis." J Virol. 1980;35:340-348. Abstract
Noordermeer J, Klingensmith J, Nusse R. "Differential requirements for segment polarity genes in wingless signaling." Mech Dev. 1995;51:145-155. Abstract
Noordermeer J, Johnston P, Rijsewijk F, Nusse R, Lawrence PA. "The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo." Development. 1992;116:711-719. Abstract
Noordermeer J, Klingensmith J, Perrimon N, Nusse R. "dishevelled and armadillo act in the wingless signalling pathway in Drosophila." Nature. 1994;367:80-83. Abstract
Nelson JW, Nusse R. "Convergence of Wnt, beta-catenin, and cadherin pathways." Science. 2004;303:1483-1487. Abstract
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Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. "Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(2):370-7. Abstract
Morrell NT, Leucht P, Zhao L, et al. "Liposomal packaging generates Wnt protein with in vivo biological activity." PLoS One. 2008;3:e2930. Abstract
Mizutani M, Wu JC, Nusse R. "Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial-to-Mesenchymal Transition." Journal of the American Heart Association. 2016;5(3):e002457. Abstract
Mirabelli CK, Nusse R, Tuveson DA, Williams BO. "Perspectives on the role of Wnt biology in cancer." Science signaling. 2019;12(589). Abstract
Minear S, Leucht P, Jiang J, et al. "Wnt proteins promote bone regeneration." Sci Transl Med. 2010;2:29ra30. Abstract
Millar SE, Willert K, Salinas PC, et al. "WNT signaling in the control of hair growth and structure." Dev Biol. 1999;207:133-149. Abstract
Mikels A, Minami Y, Nusse R. "Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling." J Biol Chem. 2009;284:30167-30176. Abstract
Mikels AJ, Nusse R. "Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context." PLoS Biol. 2006;4:e115. Abstract
Mikels AJ, Nusse R. "Wnts as ligands: processing, secretion and reception." Oncogene. 2006;25:7461-7468. Abstract
Michalides R, van Nie R, Nusse R, Hynes NE, Groner B. "Mammary tumor induction loci in GR and DBAf mice contain one provirus of the mouse mammary tumor virus." Cell. 1981;23:165-173. Abstract
Michalides R, van Ooyen A, Nusse R. "Mouse mammary tumor virus expression and mammary tumor development." Curr Top Microbiol Immunol. 1983;106:57-78.
Michalides R, van Deemter L, Nusse R, Ropcke G, Boot L. "Involvement of mouse mammary tumor virus in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains." J Virol. 1978;27:551-559. Abstract
Michalides R, Wagenaar E, Nusse R. "Autogenous antibodies against the murine mammary tumor virus in strains of mice with low incidences of mammary tumors." J Natl Cancer Inst. 1979;62:935-941. Abstract
Michalides R, van Deemter L, Nusse R, Hageman P. "Induction of mouse mammary tumor virus RNA in mammary tumors of BALB/c mice treated with urethane, X-irradiation, and hormones." J Virol. 1979;31:63-72. Abstract
Miao Y, Ha A, de Lau W, et al. "Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020. Abstract