Structure 2.1 released July 2003, updated August 2004 change log (windows patch released March 2007)
The program structure is a free software package for using multi-locus genotype data to investigate population structure. Its uses include inferring the presence of distinct populations, assigning individuals to populations, studying hybrid zones, identifying migrants and admixed individuals, and estimating population allele frequencies in situations where many individuals are migrants or admixed. It can be applied to most of the commonly-used genetic markers, including microsatellites, RFLPs and SNPs. This method was described in an article in Genetics (155: 945-959). Extensions to the method were published in Genetics 2003 (164:1567-1587). [Example], ["Time-lapse" plots].
The new version includes a new graphical front end, as well as various updates and extensions, including a model to deal with linked loci.
Registration
We ask that you fill out a web
form to register software downloads. Executables are currently available
for the following platforms.
For Windows 95/98/NT/2000/XP : [Windows][Patch].
For DOS/Windows: [DOS/Windows][Patch].
For MacOS X: [Mac
OS X]
(Thanks to Eric Anderson for compiling this)
Plotting program:
Plotting program (by Noah Rosenberg) and data used for "Genetic Structure of Human Populations" (Science Dec 2002).
Click here for installation instructions.
Please contact us to report any bugs or other problems at structure_help@genetics.uchicago.edu.