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TUTORIAL: Clinical PET - Cardiology

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Contents:
Topics:
  • Cardiac Scan Evaluation
  • Dietary Effects on FDG Metabolism
  • Parametric Imaging
  • Polar Maps
  • Single Vessel Disease
  • Double Vessel Disease
  • Myocardial Viability - Mismatch
  • Myocardial Viability - Match
  • Ischemic Dilated Cardiomyopathy
  • Idiopathic Dilated Cardiomyopathy

  • Myocardial Viability - Match


    Click on image above to view full-size image.

    The images in the top row are from a NH3 perfusion study, and the images in the bottom row are from a 18FDG metabolic study. Both the flow and metabolic images show a matching defect in the antero-septal wall. This is consistent with a perfusion deficit in the antero-septal wall. The hypometabolism supports the conclusion that there is little viable tissue in the antero-septal wall of this patient.


    Click on image above to view full-size image.

    The left image represents the polar map obtained from the previous flow images, and the right image represents the polar map obtained from the previous metabolic images. Note that the antero-septal wall in each polar map shows a deficit. This is a matched study indicating little viable tissue in the poorly perfused antero-septal wall.


    Click on image above to view full-size image.

    Depicted above is the flow-minus-metabolism polar map obtained from the flow and metabolism polar maps shown previously. Areas in red indicate mismatch. Note that this polar map is consistent with a matching defect, because there are essentially no red regions. This would once again support the conclusion that very little viable tissue is present in the poorly perfused antero-septal wall segment.

    Credits

    Material for this section was kindly provided by:

    Johannes Czernin, M.D.
    Dept. of Molecular and Medical Pharmacology
    UCLA School of Medicine

    Heinrich R. Schelbert, M.D., Ph.D.
    Dept. of Molecular and Medical Pharmacology
    UCLA School of Medicine

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