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TUTORIAL: Clinical PET - Cardiology

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Contents:
Topics:
  • Cardiac Scan Evaluation
  • Dietary Effects on FDG Metabolism
  • Parametric Imaging
  • Polar Maps
  • Single Vessel Disease
  • Double Vessel Disease
  • Myocardial Viability - Mismatch
  • Myocardial Viability - Match
  • Ischemic Dilated Cardiomyopathy
  • Idiopathic Dilated Cardiomyopathy

  • Single Vessel Disease


    Click on image above to view full-size image.

    The re-sliced NH3 perfusion and FDG metabolism images shown above are relatively normal. There is homogeneous distribution of tracer, without any significant defects in any of the imaged planes.


    Click on image above to view full-size image.

    The polar maps derived from the previous images are shown above. Note that they are consistent with a homogeneous flow pattern, as well as a relatively homogeneous metabolism pattern. The scales for each polar map are shown, and they differ. The hotter yellow areas in the lateral regions of the metabolism polar map are not significantly different from normal.


    Click on one or both of the images above to view full-size image(s).

    The same patient is now given a stress-perfusion study to look for any perfusion abnormalities under states of increased myocardial demand. The results of this study, shown above, reveal a small defect in one of the planes (look for a red arrow in the series of images in the bottom row). The polar map shows the same defect (the green pixels) in the antero-septal region.

    Credits

    Material for this section was kindly provided by:

    Johannes Czernin, M.D.
    Dept. of Molecular and Medical Pharmacology
    UCLA School of Medicine

    Heinrich R. Schelbert, M.D., Ph.D.
    Dept. of Molecular and Medical Pharmacology
    UCLA School of Medicine

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